TEER / MitraClip
for Mitral Regurgitation

A minimally invasive, catheter-based treatment for selected patients with a leaking mitral valve. TEER reduces mitral regurgitation without opening the chest.

TEER is not suitable for every patient. Treatment depends on the cause and severity of mitral regurgitation, valve anatomy, overall health and surgical risk. An individualised assessment is required.

Heart Team assessment
Valve disease treatment decisions involve input from multiple specialists.
Advanced echo imaging
3D echocardiography helps determine whether TEER is anatomically appropriate.
Catheter-based approach
The TEER device is delivered through a catheter without opening the chest.
Follow-up care included
Monitoring and clinical review continue after the procedure.

What is TEER / MitraClip?

Transcatheter Edge-to-Edge Repair — also known by the device name MitraClip


In mitral regurgitation, the mitral valve does not close properly, allowing blood to flow backwards into the left atrium with each heartbeat. This forces the heart to work harder and can cause breathlessness, fatigue and declining exercise capacity.

TEER uses a specialised clip delivered through a catheter to bring the mitral valve leaflets closer together, reducing the backward flow of blood. The procedure is performed under echocardiographic and X-ray imaging guidance — without a standard sternotomy.

  • TEER is distinct from TAVI — it treats the mitral valve, not the aortic valve
  • Catheter-based delivery, usually through a vein in the groin
  • Aims to reduce the degree of mitral regurgitation
  • Detailed 3D echocardiography is central to the procedure
  • No standard sternotomy — no heart-lung machine routinely required
Discuss Your Mitral Valve Reports

Dr Ankur Phatarpekar explains TEER, mitral regurgitation and how the Heart Team determines whether this approach is appropriate.

Common symptoms of mitral regurgitation

Mitral regurgitation can develop gradually. Some people have few or no symptoms initially, while others develop symptoms as the condition progresses. A medical evaluation is needed to confirm whether symptoms are related to valve disease.

Breathlessness symptom of mitral regurgitation
Breathlessness
Shortness of breath during activity, climbing stairs or tasks that were previously comfortable.
Reduced stamina and fatigue from mitral valve leakage
Reduced stamina
Everyday activities may leave you unusually tired or exhausted.
Ankle and leg swelling from fluid retention
Swelling
Fluid retention can cause swelling around the ankles, feet or legs.
Difficulty lying flat due to breathlessness and orthopnea
Difficulty lying flat
Increased breathlessness or coughing when lying down.
Heart palpitations and irregular heartbeats
Palpitations
A sensation of a rapid, fluttering or irregular heartbeat.
Light-headedness and dizziness from cardiac dysfunction
Light-headedness
Dizziness that may be related to how the heart is functioning.

Who may be considered for TEER?

TEER is not simply an alternative that replaces surgery for everyone with mitral valve disease. Suitability is determined by a detailed clinical and imaging assessment.

Cause of mitral regurgitation evaluation for TEER procedure
Cause of regurgitation
Whether the valve problem is primary (degenerative) or secondary (functional) affects treatment selection significantly.
Severity of mitral valve leakage and regurgitation assessment
Severity of leakage
The degree of mitral regurgitation and its effect on the heart are assessed carefully.
Mitral valve anatomy evaluation using 3D echocardiography
Valve anatomy
Not every mitral valve is anatomically suitable for TEER — detailed echocardiography determines this.
Surgical risk evaluation for TEER or MitraClip selection
Surgical risk
TEER may be considered for patients who face high or prohibitive surgical risk.
Assessment of symptoms and left ventricular function
Symptoms and heart function
Symptoms, left ventricular function and response to medical treatment all influence the assessment.
Patient overall health and frailty evaluation for TEER
Overall health and frailty
Age, other medical conditions and frailty are considered alongside valve-specific factors.

The presence of mitral regurgitation does not automatically mean TEER is required. The Heart Team reviews each case — including TEER, surgery and medical management — before any recommendation is made.

How TEER is performed

The procedure is carried out in a specialised cardiac catheterisation environment. 3D transoesophageal echocardiography plays a central role throughout.

Step 1: Venous access via the femoral vein for TEER procedure
Access
A catheter is introduced through a vein, usually in the groin, and advanced to cross the wall between the upper chambers of the heart.
Step 2: Catheter navigation toward the mitral valve under 3D echo guidance
Navigation
The catheter is carefully guided towards the mitral valve using X-ray and detailed echocardiographic imaging.
Step 3: Grasping mitral valve leaflets with the TEER MitraClip device
Grasping
The TEER device is positioned across the mitral valve and the appropriate valve leaflets are carefully grasped by the clip.
Step 4: Real-time assessment of mitral regurgitation reduction
Assessment
The team assesses the reduction in mitral regurgitation. If the result is satisfactory, the device is deployed and the catheter removed.

TEER or mitral valve surgery?

The choice between TEER and surgery depends on the type of mitral valve disease, anatomy, symptoms, heart function, age, overall health and surgical risk. One approach is not universally better than the other.

TEER (MitraClip) Mitral Valve Surgery
ApproachCatheter-based procedureSurgical procedure
AccessCatheter, usually through a vein in the groinSurgical access through the chest
Chest openingNo standard sternotomyUsually required
Heart-lung machineNot routinely requiredMay be required
SuitabilitySelected patients with suitable anatomy and clinical indicationAppropriate patients where surgery is the preferred treatment
DecisionMultidisciplinary Heart Team assessmentMultidisciplinary Heart Team assessment

The important question is not "which procedure is better?" — it is "which treatment is most appropriate for this particular patient?" A Heart Team can review your clinical condition and imaging to help determine the most suitable pathway.

What does the clinical evidence show?

The COAPT randomised trial assessed TEER with MitraClip in a specific population of patients with heart failure and significant secondary mitral regurgitation despite guideline-directed medical therapy.

Heart-failure hospitalisation — annualised rate at 2 years
35.8%
TEER
67.9%
Medical therapy
All-cause mortality at 2 years
29.1%
TEER
46.1%
Medical therapy

These figures apply to the specific COAPT study population and should not be interpreted as any individual patient's expected outcome. Results vary depending on the cause of mitral regurgitation, anatomy, heart function and other clinical factors.

Source: Stone GW, et al. Transcatheter Mitral-Valve Repair in Patients with Heart Failure. New England Journal of Medicine. 2018;379:2307–2318 (COAPT Trial). Additional reference: ACC/AHA Guideline for the Management of Patients with Valvular Heart Disease.

Dr Ankur U. Phatarpekar — Interventional Cardiologist and Structural Heart Specialist at The Valve Clinic Mumbai

Your Heart Team

Dr Ankur U. Phatarpekar
MD · DM · FSCAI
Interventional Cardiologist | Structural Heart & Valve Specialist

Dr Ankur Phatarpekar is an interventional cardiologist with expertise in complex coronary and structural heart interventions, including transcatheter valve procedures. At The Valve Clinic, he works with a multidisciplinary team to evaluate patients with heart valve disease and determine the most appropriate treatment pathway.

  • Detailed clinical assessment
  • Advanced cardiac imaging
  • Multidisciplinary Heart Team review
  • Individualised treatment planning
  • Minimally invasive treatment where appropriate
  • Follow-up after the procedure

TEER requires more than the person delivering the device. At The Valve Clinic, relevant specialists work together — including interventional cardiologists, echocardiographers, cardiac surgeons and anaesthesiologists — to ensure your case is assessed from every angle before any recommendation is made.

Frequently asked questions

TEER (Transcatheter Edge-to-Edge Repair) is the category of procedure. MitraClip is a device used for this type of repair. The terms are sometimes used interchangeably. Other devices in this category also exist. TEER treats the mitral valve and is distinct from TAVI, which treats the aortic valve.

Suitability depends on several factors, including the cause and severity of mitral regurgitation, symptoms, valve anatomy, heart function, overall health and surgical risk. A detailed clinical and imaging assessment — including echocardiography — is required before any recommendation is made.

It is not appropriate to describe TEER as universally safer than surgery. Both procedures have potential benefits and risks. TEER may be particularly appropriate for selected patients who face high or prohibitive surgical risk. The Heart Team assesses the relative risks and benefits for each individual.

The objective of TEER is to reduce mitral regurgitation, but the degree of reduction varies between patients. The final result depends on valve anatomy, the mechanism of the disease and how the heart responds to treatment. The team will discuss expected outcomes during the assessment process.

Assessment may include an echocardiogram, transoesophageal echocardiography and other imaging or investigations depending on the patient's condition. Detailed echocardiography is particularly important in determining whether the mitral valve anatomy is suitable for TEER.

The cost varies depending on the device used, hospital, procedural requirements and the patient's clinical condition. A personalised estimate can be provided after the patient's clinical information and reports have been reviewed by our team. Please contact us to discuss your specific situation.